When is the Best Time to Take Magnesium?

When is the Best Time to Take Magnesium?

Embrace the wonders of magnesium, and learn why this essential mineral might be your next powerhouse addition to a health-enhancing routine.

Magnesium. You've probably heard of it, and perhaps even spotted it on a supplement bottle or two. Yet, this essential mineral is far more than just another wellness buzzword; it’s an integral part of our health, involved in fascinating and complex biochemical reactions that help keep us functioning at our best. As we peel back the layers of magnesium's importance and determine when to best incorporate it into your routine, you're bound to gain a newfound appreciation for this mineral powerhouse.

What Exactly is Magnesium?

Magnesium is our body's unsung hero, serving as a critical co-factor in processes that regulate everything from muscle and nerve function to the synthesis of proteins, DNA, and even the RNA in our cells.(1) Imagine, this remarkable mineral is even responsible for the beat of your heart, helping it maintain a steady rhythm.(2) Just like a maestro directing an orchestra, magnesium conducts the symphony of reactions that ensure our bodies operate in harmony.

Why is Magnesium So Important?

When we talk about the importance of magnesium, it's not just about its extensive role in energy production, it's about how it manages the very building blocks of our life—our DNA and RNA.(3) It assists in the replication, repair, and continuous reading of DNA, the blueprint of life itself. Think of it as the architect in our cellular construction sites, ensuring everything runs smoothly.(4) Can you see now why it's more than just a supplement?

In the next sections, we'll dive into when it's the best time to take this amazing mineral for maximum benefits.

When is the Optimal Time to Take Magnesium?

Understanding magnesium's place in our daily regimen brings us back to the question at hand: when is the best time to consume magnesium for optimal benefit? As with most aspects of health, it's not a one-size-fits-all answer. However, based on its unique properties and our bodies' natural rhythms, many people find taking magnesium in the evening to be particularly effective.(5)

Why is Evening Often Considered the Best Time to Take Magnesium?

There's a good reason why magnesium has earned a reputation as a sort of 'natural chill pill'. You see, magnesium has some solid research backing its sleep-enhancing and relaxation properties.(6) For instance, it can increase the neurotransmitter GABA, which promotes relaxation and sleep.(7) It's no surprise, then, that magnesium is often invited to the evening routine.

But what about the relationship between magnesium and meals? Well, some forms of magnesium are best taken with food to aid absorption, while others can be taken with or without food.(8) It's always best to follow the instructions on the product's label or consult your healthcare provider.

Specifically, if you take magnesium in the evening, you might consider consuming it with dinner or shortly after. As the body's absorption of magnesium may be optimized during rest due to our natural circadian rhythms, coupling it with your last meal of the day can be quite advantageous.(9)

So, what's the takeaway here? While the timing of your magnesium intake should ultimately be based on your individual needs, consuming it in the evening, potentially with a meal, is a practice backed by many.


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(1) Swaminathan, R. "Magnesium Metabolism and Its Disorders." The Clinical Biochemist Reviews 24, no. 2 (2003): 47–66.

(2) Jahnen-Dechent, Wilhelm, and Markus Ketteler. "Magnesium basics." Clinical kidney journal 5, no. Suppl_1 (2012): i3-i14.

(3) Ohsawa, Masaki, Hideyuki Fujioka, and Takehiko Saito. "Novel Function of Magnesium: Contribution to DNA Replication." Biol. Pharm. Bull. 44, no. 3 (2021): 323-328.

(4) Gröber, Uwe, Joachim Schmidt, and Klaus Kisters. "Magnesium in Prevention and Therapy." Nutrients 7, no. 9 (2015): 8199–8226.

(5) Boyle, Neil B., Clare Lawton, and Louise Dye. "The Effects of Magnesium Supplementation on Subjective Anxiety and Stress—A Systematic Review." Nutrients 9, no. 5 (2017): 429.

(6) Nielsen, Forrest H., Henry C. Lukaski, and LuAnn K. Johnson. "Involvement of Dietary Magnesium and Intestinal Magnesium Absorption in Sleep." Minerals 10, no. 1 (2020): 84.

(7) Gromova, Olga A., and Ivan I. Torshin. "Mechanisms of the "Anti-Stress" Activity of Magnesium Compounds." Neurochemical Journal 14, no. 1 (2020): 81-90.

(8) Schwalfenberg, Gerry, and Stephen J Genuis. "The Importance of Magnesium in Clinical Healthcare." Scientifica 2017 (2017): 4179326.

(9) Ayuk, John, and Neil Gittoes. "Contemporary view of the clinical relevance of magnesium homeostasis." Annals of Clinical Biochemistry 51, no. 2 (2014): 179-188.

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